@InProceedings{Kaldoudi_EMBEC_2024, author = {Kaldoudi, Eleni and Marozas, Vaidotas and Rytis, Jurkonis and Pousset, Nicolas and Legros, Mathieu and Kircher, Marco and Novikov, Dmitry and Sakalauskas, Andrius and Moustakidis, Pavlos and Ayinde, Babajide and Moltani, Lara Alessia and Balling, Susann and Vehkaoja, Antti and Oksala, Niku and Macas, Andrius and Balciuniene, Neringa and Bigaki, Maria and Potoupnis, Michail and Papadopoulou, Stella-Lida and Grandone, Elvira and Gautier, Maxime and Bouda, Sabrina and Schloetelburg, Cord and Prinz, Thorsten and Dionisio, Pietro and Anagnostopoulos, Spyridon and Drougka, Ioanna and Folkvord, Frans and Drosatos, George and Didaskalou, Stylianos and {The ThrombUS+ Consortium}}, editor = {Jarm, Toma{\v{z}} and {\v{S}}merc, Rok and Mahni{\v{c}}-Kalamiza, Samo}, title = {Towards Wearable Continuous Point-of-Care Monitoring for Deep Vein Thrombosis of the Lower Limb}, booktitle = {9th European Medical and Biological Engineering Conference}, year = {2024}, publisher = {Springer Nature Switzerland}, address = {Cham}, pages = {326--335}, doi = {10.1007/978-3-031-61628-0_36}, url = {https://doi.org/10.1007/978-3-031-61628-0_36}, abstract = {Deep vein thrombosis (DVT) is the formation of a blood clot within the deep veins, most commonly those of the lower limbs, causing obstruction of blood flow. In 50{\%} of people with DVT, the clot eventually breaks off and travels to the lung to cause pulmonary embolism. Clinical assessment of DVT is notoriously unreliable because up to 2/3 of DVT episodes are clinically silent and patients are symptom free even when pulmonary embolism has developed. Early diagnosis of DVT is crucial, and despite the progress made in ultrasound imaging and plethysmography techniques, there is a need for new methods to enable continuous monitoring of DVT at the point of care. This paper presents the conceptual design and methodology towards a novel wearable diagnostic device for point-of-care, operator-free, continuous monitoring in patients with high DVT risk. The device will combine novel wearable hardware for ultrasound imaging and impedance plethysmography with autonomous, AI driven DVT detection, to allow continuous monitoring for blood clot formation in the lower limb. Activity and other physiological measurements will be used to provide a continuous assessment of DVT risk and guide the automated scanning via an intelligent decision support unit that will provide accurate monitoring and alerts. The work is supported by the Horizon project ThrombUS+ co-funded by the European Union. (Grant Agreement No. 101137227).}, isbn = {978-3-031-61628-0} }